Portland Timbers v Vancouver Whitecaps
Portland Timbers: Kalif Alhassan (15/1 m), Steve Zakuani (17/0 m) (both doubtful)
Vancouver Whitecaps: Andre Lewis (0/0 m), Caleb Clarke (0/0 f), Gershon Koffie (20/1 m)
Philadelphia Union v Houston Dynamo
Philadelphia Union: –
Houston Dynamo: Tony Cascio (5/0 m), Mark Sherrod (9/2 f), Tally Hall (24/0 first goalkeeper), Will Bruin (24/10 f, top scorer), Jermaine Taylor (21/0 d), Boniek Garcia (23/1 m), Corey Ashe (20/0 d)
Columbus Crew v New England Revolution
Columbus Crew: Federico Higuain (25/9 f, top scorer), Adam Bedell (16/2 f) (both doubtful), Kingsley Baiden (1/0 m), Matt Wiet (0/0 d), Josh Williams (14/0 d), Daniel Paladini (4/0 m)
New England Revolution: Jermaine Jones (4/0 m), Shalrie Joseph (0/0 m) (both doubtful), Teal Bunbury (28/4 f), Andy Dorman (15/0 m), Stephen McCarthy (1/0 d)
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