Athletic Bilbao v Deportivo Alavés
Athletic Bilbao: Yeray (10/0 d), Lekue (9/0 d), De Marcos (9/0 m), Aketxe (0/0 m)
Deportivo Alavés: Hernández (14/0 d, suspended), Alexis (12/1 d)
Real Betis v CD Leganés
Real Betis: Gutiérrez (12/1 m), Joaquín (15/3 m, 2nd top scorer)
CD Leganés: Herrerín (3/0 2nd goalkeeper, suspended), Serantes (13/0 first goalkeeper), Diego Rico (11/1 d), Ibáñez (5/2 m, 2nd top scorer), Szymanowski (10/3 m, top scorer), Koné (5/0 f)
Celta de Vigo v Málaga CF
Celta de Vigo: Roncaglia (14/2 d), Planas (2/0 d), Orellana (7/2 m), Beauvue (0/0 f)
Málaga CF: Koné (7/0 d, national selection), Kuzmanovic (4/0 m), En-Nesyri (10/1 f, national selection)
Villarreal CF v FC Barcelona
Villarreal CF: Cheryshev (8/0 m), Soldado (0/0 f)
FC Barcelona: Cillessen (1/0 g), Rakitic (12/2 m)
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