Liverpool FC v Villarreal CF
Liverpool FC: Mamadou Sakho (22/1 d, UEFA suspension), John Flanagan (3/0 d), Divock Origi (16/5 f), Jordan Henderson (16/2 m), Jordan Rossiter (1/0 m), Joe Gomez (5/0 d), Danny Ings (5/2 f), Connor Randall (2/0 m)
Villarreal CF: no absences
Sevilla FC v Shakhtar Donetsk
Sevilla FC: Reyes (24/1 m), Kolodziejczak (27/0 d), Andreolli (7/0 d), Krohn-Dehli (27/1 m)
Shakhtar Donetsk: Srna (19/2 d), Dentinho (13/2 m), Gladkiy (16/3 f)(all doubtful), Fred (12/2 m, UEFA suspension), Azevedo (6/0 d)
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